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The role of the endothelium in ED has been noted for a number of years and the overlapping of ED and other conditions, especially coronary heart disease, CVD, affecting endothelial function/dysfunction, is clearly present. The endothelial cell is now known to affect vascular tone and impact the process of atherosclerosis, and impacting ED, CVD and peripheral vascular disease.16

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When a man has problems with erections, it is sometimes difficult to know if the cause(s) are physical, psychological, or both. The nocturnal penile tumescence (NPT) test can give the doctor some clues.
A number of devices have been developed to determine if an erection occurs during sleep. This snap gauge is fastened around the penis but opens when an erection occurs. Click to view larger image. .

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Men being treated for prostate cancer with treatments such as radical prostatectomy, radiation therapy or the use of Lutenizing hormone-releasing hormone (LHRH) agonists and antagonists can expect that ED may accompany these treatments.12
Nebivolol seems to have an advantage over other beta-blockers when used to treat men with hypertension and ED. It has additional vasodilating effects because it stimulates endothelial release of nitric oxide (NO), resulting in relaxation of smooth muscle in the corpus cavernosum, allowing penile erection.25 Despite limited studies, nebivolol does not seem to worsen erectile function and some studies have demonstrated significant improvement in erectile function with nebivolol compared with second-generation cardioselective beta-blockers.23,26–28

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Several medications can interfere with the chemical processing of PDE5i medications by the liver. These can include ketoconazole (an antifungal medication known by the brand name Nizoral), erythromycin (an antibiotic), and cimetidine (also known as Tagamet, for reducing stomach acid). A lower dose of PDE5i medications should be used if one is taking any of these medications.

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Erectile dysfunction (ED) is one of the most common conditions affecting middle-aged and older men. Nearly every primary care physician, internist and geriatrician will be called upon to manage this condition or to make referrals to urologists, endocrinologists and cardiologists who will assist in the treatment of ED. This article will briefly discuss the diagnosis and management of ED. In addition, emerging concepts in ED management will be discussed, such as the use of testosterone to treat ED, the role of the endothelium in men with ED and treating the partner of the man with ED. Finally, future potential therapies for ED will be discussed.

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Some men experience symptoms only occasionally. For others, the symptoms are constant and interfere with their sexual relationships.

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    All clinical services and programs are part of University of Utah Health Hospitals and Clinics.

    This patient education application provides patients and Health Care Practitioners with easy to access information on Erectile Dysfunction management. The developer, BuiltByDoctors, has not provided details about its privacy practices and handling of data to Apple.
    For some people, this is a delicate talking point to go about asking our friends, neighbours, family members or even the doctor! I believe that the first step we should do when facing a situation like this is to bear in mind that this is quite normal and to get informed. For this reason, I believe that this reader is helpful. Nevertheless, I am of the opinion that apart from reading this book, an appointment with the doctor is a must for those people going through this type of situation.

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    Response is dose related and usually occurs within 10–15 min, and does not require stimulation. The intraurethral preparation, medicated urethral suppository for erection (MUSE), consists of a tiny pellet of drug inserted into the urethral meatus. Response is also dose related, and onset similar to the cavernosal preparations.

    The risk of having ED after prostate cancer treatment depends on the surgical technique or type of radiation used by your doctor, but also on your:
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    Not everyone can use these medicines. Your doctor may talk to you about alprostadil if oral medicines aren’t an option for you. Alprostadil is a synthetic version of prostaglandin E. It can be injected into the penis or inserted as a tiny suppository into the urethra (the hole at the end of the penis). Your doctor will help you decide which treatment is best for you.

    Lifestyle choices can contribute to ED. Smoking, heavy drinking, and drug use disorder can damage the blood vessels and reduce blood flow to your penis. Being overweight and getting too little exercise also raise your odds. Studies show that men who exercise regularly have a lower risk of ED.
    Men need a lot of different body parts working the right way -- from the brain and glands that control hormones to blood vessels and the penis -- to get and keep an erection. Because of that, erectile dysfunction, or ED, can have a lot of causes. Some of them are physical; others are mental and emotional.

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    Radiation for prostate cancer can cause ED symptoms to appear gradually, usually within two to three years after treatment. If you are experiencing ED after undergoing prostate cancer treatment, you can get a healthy sex life back. We can help you choose the best treatment options for you. By Name By Location ED Treatments pills, injections, penile suppositories, vacuum devices, shockwave therapy, and surgery.
    Problems faced by urologists at all stages when returning to surgery after a prolonged absence

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Mild and moderate ED affects about 10 percent of men per decade of life. That means 50 percent of men in their fifties suffer, 60 percent of men in their sixties, and so on.

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Men in their 40s with erectile dysfunction (ED) compared with men without a history of ED have an increased risk of developing cardiovascular disease (CVD) in 5 years.

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Currently, there are several different types of penile prostheses. The simplest is the malleable penile prosthesis and the most complex, the three-piece inflatable penile prosthesis.

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